OSGIN1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for OSGIN1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2728069)
Target
See all OSGIN1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This OSGIN1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Oxidative stress induced growth inhibitor 1 (OSGIN1), transcript variant 1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- OSGIN1 (Oxidative Stress Induced Growth Inhibitor 1 (OSGIN1))
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Background
- This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product.
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Molecular Weight
- 60.7 kDa
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NCBI Accession
- NP_037502
Target
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