PANK1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728200

This Recombinant PANK1 protein is produced in HEK-293 Cells.

Quick Overview for PANK1 Protein (Myc-DYKDDDDK Tag) (ABIN2728200)

Target: PANK1 (Pantothenate Kinase 1 (PANK1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This PANK1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human PANK1 / PANK (transcript variant gamma) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PANK1 (Pantothenate Kinase 1 (PANK1))

Alternative Name: Pank1,pank

Background: This gene encodes a member of the pantothenate kinase family. Pantothenate kinases are key regulatory enzymes in the biosynthesis of coenzyme A (CoA). The encoded protein catalyzes the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene and an intronic miRNA on the same strand are co-regulated by the tumor suppressor p53 (see PMID 20833636).

Molecular Weight: 35.4 kDa

NCBI Accession: NP_612189

Pathways: Ribonucleoside Biosynthetic Process