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Paired Box 3 Protein (PAX3) (Myc-DYKDDDDK Tag)

This Recombinant Paired Box 3 protein is produced in HEK-293 Cells.
Catalog No. ABIN2728311

Quick Overview for Paired Box 3 Protein (PAX3) (Myc-DYKDDDDK Tag) (ABIN2728311)

Target

See all Paired Box 3 (PAX3) Proteins
Paired Box 3 (PAX3)

Protein Type

Recombinant

Origin

  • 5
  • 2
  • 1
  • 1
Human

Source

  • 2
  • 2
  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This Paired Box 3 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human PAX3 (transcript variant PAX3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
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    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    Paired Box 3 (PAX3)

    Alternative Name

    Pax3

    Background

    This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(213)(q35q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

    Molecular Weight

    52.8 kDa

    NCBI Accession

    NP_852122

    Pathways

    Sensory Perception of Sound, Tube Formation
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