Paired Box 3 Protein (PAX3) (His tag)
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- Target See all Paired Box 3 (PAX3) Proteins
- Paired Box 3 (PAX3)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Paired Box 3 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PAX3 (N-term HIS tag, transcript variant PAX3D) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PAX3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Paired Box 3 (PAX3)
- Alternative Name
- Pax3 (PAX3 Products)
- Synonyms
- PAX3 Protein, cdhs Protein, hup2 Protein, pax-3 Protein, ws1 Protein, xpax3 Protein, Pax3 Protein, pax3 Protein, pax3b Protein, xPax3-B Protein, CDHS Protein, HUP2 Protein, WS1 Protein, WS3 Protein, Pax-3 Protein, Sp Protein, splotch Protein, zgc:92547 Protein, paired box 3 Protein, paired box 3 L homeolog Protein, paired box 3a Protein, PAX3 Protein, pax3 Protein, pax3.L Protein, Pax3 Protein, pax3a Protein
- Background
- This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(213)(q35q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
- Molecular Weight
- 53.3 kDa
- NCBI Accession
- NP_852123
- Pathways
- Sensory Perception of Sound, Tube Formation
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