KAT2B Protein (DYKDDDDK Tag)
Quick Overview for KAT2B Protein (DYKDDDDK Tag) (ABIN2728344)
Target
See all KAT2B ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This KAT2B protein is labelled with DYKDDDDK Tag.
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Characteristics
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- Recombinant human PCAF / KAT2B (full length, C-term DDK tag) protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 20 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
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Alternative Name
- Pcaf,kat2b
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Background
- CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
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Molecular Weight
- 93 kDa
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NCBI Accession
- NP_003875
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Pathways
- p53 Signaling, Regulation of Carbohydrate Metabolic Process
Target
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