PDE4B Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)
Quick Overview for PDE4B Protein (Transcript Variant A) (Myc-DYKDDDDK Tag) (ABIN2728515)
Target
See all PDE4B ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant A
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Purification tag / Conjugate
- This PDE4B protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human PDE4B (transcript variant a) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
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Alternative Name
- Pde4b
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Background
- This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.
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Molecular Weight
- 83.2 kDa
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NCBI Accession
- NP_002591
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Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
Target
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