PDIA3 Protein (Myc-DYKDDDDK Tag)
Quick Overview for PDIA3 Protein (Myc-DYKDDDDK Tag) (ABIN2728557)
Target
See all PDIA3 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This PDIA3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human PDIA3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
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Alternative Name
- Pdia3
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Background
- This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates.
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Molecular Weight
- 54.2 kDa
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NCBI Accession
- NP_005304
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Pathways
- Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
Target
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