PDIA6 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728569

Product Details

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PDIA6 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PDIA6 / P5 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Alternative Name: Pdia6,p5 (PDIA6 Products)

Synonyms: 1700015E05Rik Protein, AL023058 Protein, C77895 Protein, CaBP5 Protein, P5 Protein, Txndc7 Protein, ERP5 Protein, TXNDC7 Protein, CaBP1 Protein, pdi-p5 Protein, erp5 Protein, pdia6 Protein, pdip5 Protein, txndc7 Protein, protein disulfide isomerase family A member 6 Protein, protein disulfide isomerase associated 6 Protein, protein disulfide isomerase family A, member 6 Protein, protein disulfide isomerase family A member 6 L homeolog Protein, PDIA6 Protein, Pdia6 Protein, pdia6.L Protein

Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 47.9 kDa

NCBI Accession: NP_005733

Pathways: ER-Nucleus Signaling, Cell RedoxHomeostasis