PLGF Protein (Transcript Variant 1)
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- Target See all PLGF (PGF) Proteins
- PLGF (PGF) (Placenta Growth Factor (PGF))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Application
- Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human Placenta growth factor / PGF (transcript variant 1) protein expressed in HEK293.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % , as determined by Coomassie stained SDS-PAGE.
- Endotoxin Level
- Less than 0.01 ng per μg protein as determined by the LAL method.
- Biological Activity Comment
- The ED50 is 1-3 ng/ml, corresponding to a specific activity of 0.33 - 1 x 106 units/mg, determined by the dose dependent binding to VEGFR1-Fc chimera using a functional ELISA.
- Top Product
- Discover our top product PGF Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Concentration
- > 50 μg/mL
- Buffer
- 5 mM citric acid, 0.15 M NaCl, 5 mM NaHPO4, pH 4.0
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PLGF (PGF) (Placenta Growth Factor (PGF))
- Alternative Name
- Placenta Growth Factor,pgf (PGF Products)
- Synonyms
- D12S1900 Protein, PGFL Protein, PLGF Protein, PlGF-2 Protein, SHGC-10760 Protein, AI854365 Protein, PIGF Protein, Plgf Protein, PlGF Protein, placental growth factor Protein, placenta growth factor Protein, PGF Protein, Pgf Protein, PLGF Protein
- Background
- This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011].
- Molecular Weight
- 14.5 kDa
- NCBI Accession
- NP_002623
- Pathways
- VEGFR1 Specific Signals
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