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PMVK Protein (Myc-DYKDDDDK Tag)

This Recombinant PMVK protein is expressed in HEK-293 Cells.
Catalog No. ABIN2729227

Quick Overview for PMVK Protein (Myc-DYKDDDDK Tag) (ABIN2729227)

Target

See all PMVK Proteins
PMVK (Phosphomevalonate Kinase (PMVK))

Protein Type

Recombinant

Origin

  • 7
  • 2
  • 1
  • 1
Human

Source

  • 4
  • 2
  • 2
  • 2
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification tag / Conjugate

    This PMVK protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human PMVK protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    PMVK (Phosphomevalonate Kinase (PMVK))

    Alternative Name

    Pmvk

    Background

    This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.

    Molecular Weight

    21.8 kDa

    NCBI Accession

    NP_006547
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