PMVK Protein (Myc-DYKDDDDK Tag)
Quick Overview for PMVK Protein (Myc-DYKDDDDK Tag) (ABIN2729227)
Target
See all PMVK ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This PMVK protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human PMVK protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PMVK (Phosphomevalonate Kinase (PMVK))
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Alternative Name
- Pmvk
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Background
- This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.
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Molecular Weight
- 21.8 kDa
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NCBI Accession
- NP_006547
Target
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