PRMT6 Protein (Myc-DYKDDDDK Tag)
Quick Overview for PRMT6 Protein (Myc-DYKDDDDK Tag) (ABIN2729674)
Target
See all PRMT6 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This PRMT6 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human PRMT6 / HRMT1L6 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PRMT6 (Protein Arginine Methyltransferase 6 (PRMT6))
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Alternative Name
- Prmt6,hrmt1l6
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Background
- The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.
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Molecular Weight
- 41.8 kDa
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NCBI Accession
- NP_060607
Target
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