PPM1L Protein (Myc-DYKDDDDK Tag)
Quick Overview for PPM1L Protein (Myc-DYKDDDDK Tag) (ABIN2729816)
Target
See all PPM1L ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This PPM1L protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Protein phosphatase 1L / PPM1L protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PPM1L (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L (PPM1L))
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Alternative Name
- Protein Phosphatase 1l,ppm1l
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Background
- The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 40.9 kDa
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NCBI Accession
- NP_640338
Target
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