ARHGAP8 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for ARHGAP8 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2730842)
Target
See all ARHGAP8 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This ARHGAP8 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human ARHGAP8 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- ARHGAP8 (rho GTPase Activating Protein 8 (ARHGAP8))
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Background
- This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.
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Molecular Weight
- 49.6 kDa
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NCBI Accession
- NP_851852
Target
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