RNASEH2B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2730890

Recombinant RNASEH2B protein expressed in HEK-293 Cells.

Quick Overview for RNASEH2B Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2730890)

Target: RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 2

Purification tag / Conjugate: This RNASEH2B protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Ribonuclease H2, subunit B (RNASEH2B), transcript variant 2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))

Background: RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).

Molecular Weight: 28.8 kDa

NCBI Accession: NP_001135751