RNASEH2A Protein (Myc-DYKDDDDK Tag)
Quick Overview for RNASEH2A Protein (Myc-DYKDDDDK Tag) (ABIN2730998)
Target
See all RNASEH2A ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This RNASEH2A protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human RNASEH2A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Ribonuclease H2, Subunit A (RNASEH2A) (AA 1-299) protein (His tag)
custom-made RNASEH2A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Ribonuclease H2, Subunit A (RNASEH2A) (AA 1-299) protein (GST tag)RNASEH2A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))
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Alternative Name
- Rnaseh2a
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Background
- The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009].
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Molecular Weight
- 33.2 kDa
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NCBI Accession
- NP_006388
Target
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