RNMTL1 Protein (Myc-DYKDDDDK Tag)
Quick Overview for RNMTL1 Protein (Myc-DYKDDDDK Tag) (ABIN2731051)
Target
See all RNMTL1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This RNMTL1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human RNMTL1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- RNMTL1 (RNA Methyltransferase Like 1 (RNMTL1))
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Alternative Name
- Rnmtl1
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Background
- Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 46.8 kDa
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NCBI Accession
- NP_060616
Target
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