ROR1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
(1 reference)Quick Overview for ROR1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2731082)
Target
See all ROR1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This ROR1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human ROR1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 30-403) (Active) protein (His-Avi Tag)
ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 30-403) protein (His tag)ROR1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 39-151) (Active) protein (His tag)ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 30-403) (Active) protein (Biotin,His-Avi Tag)ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 30-305) (Active) protein (His tag)ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 30-403) (Active) protein (hFc Tag)ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 165-305) (Active) protein (His tag)ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 22-477) (Active) protein (His tag)ROR1 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 30-406) (Active) protein (His tag)ROR1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) (AA 308-395) (Active) protein (His tag)ROR1 Origin: Human, Cynomolgus, Rhesus Monkey Host: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142310, (2015) (PubMed).
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- ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
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Alternative Name
- Ror1
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Background
- This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Molecular Weight
- 104.1 kDa
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NCBI Accession
- NP_005003
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Pathways
- RTK Signaling, WNT Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
Target
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