FAP Protein (Myc-DYKDDDDK Tag)
Quick Overview for FAP Protein (Myc-DYKDDDDK Tag) (ABIN2731674)
Target
See all FAP ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This FAP protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Seprase / FAP protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- FAP (Fibroblast Activation Protein, alpha (FAP))
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Alternative Name
- Seprase,fap
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Background
- The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 87.5 kDa
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NCBI Accession
- NP_004451
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Pathways
- Tube Formation
Target
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