FAP Protein (AA 26-760) (His tag)
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- Target See all FAP Proteins
- FAP (Fibroblast Activation Protein, alpha (FAP))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 26-760
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FAP protein is labelled with His tag.
- Characteristics
- Human FAP Protein, His Tag (MALS verified) (active enzyme)
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product FAP Protein
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Fibroblast Activation Protein, alpha (FAP) (AA 26-760) protein (Fc Tag)
FAP Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) protein (His-Avi Tag,Biotin)FAP Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) (AA 26-761) protein (His tag)FAP Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Fibroblast Activation Protein, alpha (FAP) (AA 26-760) protein (His tag)FAP Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) protein (His tag)FAP Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) (AA 26-760) protein (His-Avi Tag,Biotin)FAP Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) (AA 26-760) (Active) protein (Fc Tag)FAP Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fibroblast Activation Protein, alpha (FAP) (Active) protein (His tag)FAP Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >90 % as determined by reducing SDS-PAGE. Active
Fibroblast Activation Protein, alpha (FAP) (AA 525-624) protein (GST tag)FAP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Fibroblast Activation Protein, alpha (FAP) protein (mFc Tag)FAP Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Powder
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- FAP (Fibroblast Activation Protein, alpha (FAP))
- Alternative Name
- FAP (FAP Products)
- Synonyms
- fap-A Protein, gene 13 Protein, FAP Protein, fapa Protein, dppiv Protein, seprase Protein, DPPIV Protein, FAPA Protein, fibroblast activation protein Protein, fibroblast activation protein alpha L homeolog Protein, fibroblast activation protein alpha Protein, fibroblast activation protein, alpha Protein, prolyl endopeptidase FAP Protein, Fap Protein, fap.L Protein, FAP Protein, fap Protein, LOC100547273 Protein
- Background
- FAP (also known as seprase) is a Type II transmembrane serine protease. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences. Degrade also gelatin, heat-denatured type I collagen. Also has dipeptidyl peptidase activity, with a preference for Ala-Pro, Ile-Pro, Gly-Pro, Arg-Pro and Pro-Pro. The plasma membrane form, in association with either DPP4, PLAUR or integrins, is involved in the pericellular proteolysis of the extracellular matrix (ECM), and hence promotes cell adhesion, migration and invasion through the ECM. Promotes glioma cell invasion through the brain parenchyma by degrading the proteoglycan brevican. Acts as a tumor suppressor in melanocytic cells through regulation of cell proliferation and survival in a serine protease activity-independent manner.
- Molecular Weight
- 86.9 kDa
- Pathways
- Tube Formation
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