SERPINB2 Protein (Transcript Variant 2)
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- Target See all SERPINB2 Proteins
- SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human SERPINB2 / PAI2 (transcript variant 2) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37C. Half maximal inhibition against 1.0 ug/mL of single chain tPA was obtained at a concentration of 1.0 ug/mL
- Top Product
- Discover our top product SERPINB2 Protein
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Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415) protein (GST tag)
SERPINB2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-100) protein (GST tag)SERPINB2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415) protein (Strep Tag)Crystallography grade SERPINB2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415) protein (Strep Tag)Crystallography grade SERPINB2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
- Alternative Name
- Serpinb2,pai2 (SERPINB2 Products)
- Synonyms
- HsT1201 Protein, PAI Protein, PAI-2 Protein, PAI2 Protein, PLANH2 Protein, SERPINB2 Protein, Planh2 Protein, ovalbumin Protein, Pai2a Protein, serpin family B member 2 Protein, serpin peptidase inhibitor, clade B (ovalbumin), member 2 Protein, serine (or cysteine) peptidase inhibitor, clade B, member 2 Protein, SERPINB2 Protein, Serpinb2 Protein
- Target Type
- Amino Acid
- Background
- Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 45.6 kDa
- NCBI Accession
- NP_002566
- Pathways
- Autophagy
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