SERPINC1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2731823

Recombinant SERPINC1 protein expressed in HEK-293 Cells.

Quick Overview for SERPINC1 Protein (Myc-DYKDDDDK Tag) (ABIN2731823)

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This SERPINC1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human SERPINC1 / Antithrombin-III protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Alternative Name: Serpinc1,antithrombin-III

Background: The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

Molecular Weight: 49 kDa

NCBI Accession: NP_000479