SH2B2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2731946

Recombinant SH2B2 protein expressed in HEK-293 Cells.

Quick Overview for SH2B2 Protein (Myc-DYKDDDDK Tag) (ABIN2731946)

Target: SH2B2 (SH2B Adaptor Protein 2 (SH2B2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This SH2B2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human SH2B2 / APS protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SH2B2 (SH2B Adaptor Protein 2 (SH2B2))

Alternative Name: Sh2b2,aps

Background: The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt&aposs lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.

Molecular Weight: 72.1 kDa

NCBI Accession: NP_066189

Pathways: Carbohydrate Homeostasis, Brown Fat Cell Differentiation