SH3BP2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for SH3BP2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2731972)
Target
See all SH3BP2 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This SH3BP2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human SH3BP2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
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Alternative Name
- Sh3bp2
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Background
- The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 62.1 kDa
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NCBI Accession
- NP_003014
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Pathways
- TCR Signaling
Target
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