Catalog No. ABIN2732105
$1,112.40
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20 μg
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Quick Overview for SKAP2 Protein (Myc-DYKDDDDK Tag) (ABIN2732105)
Target
See all SKAP2 Proteins
SKAP2
(Src Kinase Associated Phosphoprotein 2 (SKAP2))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Purification tag / Conjugate
- This SKAP2 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human SKAP2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Src Kinase Associated Phosphoprotein 2 (SKAP2) (AA 1-359) protein (GST tag)
SKAP2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))
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Alternative Name
- Skap2
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Background
- The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Molecular Weight
- 41 kDa
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NCBI Accession
- NP_003921
Target
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