Quick Overview for SOCS3 Protein (Myc-DYKDDDDK Tag) (ABIN2732342)
Target
See all SOCS3 ProteinsProtein Type
Origin
Source
Application
Purity
-
-
Purification tag / Conjugate
- This SOCS3 protein is labelled with Myc-DYKDDDDK Tag.
-
Characteristics
-
- Recombinant human SOCS3 / CIS3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!ProductExpression SystemConjugateOriginPrice starts atExpression System Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin HumanPrice starts at $20,480.57Your project requires further customization? Contact us and discover our custom protein solutions
-
Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) protein (GST tag)
SOCS3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) protein (His-IF2DI Tag)SOCS3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) (Active) protein (His tag)SOCS3 Origin: Mouse Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
-
-
Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
-
The tag is located at the C-terminal.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 50 μg/mL
-
Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
-
Storage
- -80 °C
-
Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
-
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
-
Alternative Name
- Socs3,cis3
-
Background
- This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
-
Molecular Weight
- 24.6 kDa
-
NCBI Accession
- NP_003946
-
Pathways
- JAK-STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
Target
-
