SOCS4 Protein (His tag)

Catalog No. ABIN2732343

This Recombinant SOCS4 protein is produced in Escherichia coli (E. coli).

Quick Overview for SOCS4 Protein (His tag) (ABIN2732343)

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This SOCS4 protein is labelled with His tag.

Characteristics:

• Recombinant human SOCS4 (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Alternative Name: Socs4

Background: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 50.4 kDa

NCBI Accession: NP_955453

Pathways: JAK-STAT Signaling, EGFR Signaling Pathway