SOCS6 Protein (His tag)
Quick Overview for SOCS6 Protein (His tag) (ABIN2732346)
Target
See all SOCS6 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This SOCS6 protein is labelled with His tag.
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Characteristics
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- Recombinant human SOCS6 / CIS4 (full length, N-term HIS tag) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
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Suppressor of Cytokine Signaling 6 (SOCS6) (AA 1-533) protein (His tag)
custom-made SOCS6 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Suppressor of Cytokine Signaling 6 (SOCS6) (AA 1-535) protein (His tag)custom-made SOCS6 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Suppressor of Cytokine Signaling 6 (SOCS6) (AA 1-535) protein (GST tag)SOCS6 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the N-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
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Alternative Name
- Socs6,cis4
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Background
- The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
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Molecular Weight
- 59.5
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NCBI Accession
- NP_004223
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Pathways
- JAK-STAT Signaling, Carbohydrate Homeostasis
Target
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