SNX15 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732393

Recombinant SNX15 protein expressed in HEK-293 Cells.

Quick Overview for SNX15 Protein (Transcript Variant A) (Myc-DYKDDDDK Tag) (ABIN2732393)

Target: SNX15 (Sorting Nexin 15 (SNX15))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant A

Purification tag / Conjugate: This SNX15 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Sorting nexin-15 (SNX15) (transcript variant A) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SNX15 (Sorting Nexin 15 (SNX15))

Alternative Name: Sorting Nexin-15 (Snx15)

Background: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

Molecular Weight: 38.1 kDa

NCBI Accession: NP_037438