Catalog No. ABIN2732708
$1,112.40
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20 μg
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United States
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Quick Overview for SSRP1 Protein (Myc-DYKDDDDK Tag) (ABIN2732708)
Target
See all SSRP1 Proteins
SSRP1
(Structure Specific Recognition Protein 1 (SSRP1))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Purification tag / Conjugate
- This SSRP1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human SSRP1 / FACT80 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Structure Specific Recognition Protein 1 (SSRP1) (AA 1-709) protein (GST tag)
SSRP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
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Alternative Name
- Ssrp1,fact80
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Background
- The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.
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Molecular Weight
- 80.9 kDa
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NCBI Accession
- NP_003137
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Pathways
- Chromatin Binding
Target
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