STAM2 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732751

This Recombinant STAM2 protein is produced in HEK-293 Cells.

Quick Overview for STAM2 Protein (Myc-DYKDDDDK Tag) (ABIN2732751)

Target: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This STAM2 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human STAM2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Alternative Name: Stam2

Background: The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.

Molecular Weight: 58 kDa

NCBI Accession: NP_005834

Pathways: EGFR Signaling Pathway, EGFR Downregulation