STON1 Protein (Myc-DYKDDDDK Tag)
Quick Overview for STON1 Protein (Myc-DYKDDDDK Tag) (ABIN2732897)
Target
See all STON1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This STON1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human Stonin-1 / SALF protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- STON1 (Stonin 1 (STON1))
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Alternative Name
- Stonin-1,salf
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Background
- Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Read-through transcription of this gene into the neighboring downstream gene, which encodes TFIIA-alpha/beta-like factor, generates a transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 83 kDa
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NCBI Accession
- NP_006864
Target
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