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T-Bet Protein (Myc-DYKDDDDK Tag)

Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2733309
  • Target See all T-Bet Proteins
    T-Bet
    Protein Type
    Recombinant
    Origin
    • 6
    • 2
    • 1
    Human
    Source
    • 4
    • 3
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This T-Bet protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human TBX21 / TBET protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product T-Bet Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    T-Bet
    Alternative Name
    Tbx21,tbet (T-Bet Products)
    Synonyms
    T-PET Protein, T-bet Protein, TBET Protein, TBLYM Protein, TBT1 Protein, Tbet Protein, Tblym Protein, T-box 21 Protein, TBX21 Protein, Tbx21 Protein
    Background
    This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells.
    Molecular Weight
    58.1 kDa
    NCBI Accession
    NP_037483
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