IL27 Receptor alpha Protein (Myc-DYKDDDDK Tag)
Quick Overview for IL27 Receptor alpha Protein (Myc-DYKDDDDK Tag) (ABIN2733333)
Target
See all IL27 Receptor alpha (IL27RA) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This IL27 Receptor alpha protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TCCR / IL27RA protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))
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Alternative Name
- Tccr,il27ra
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Background
- In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
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Molecular Weight
- 69.3 kDa
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NCBI Accession
- NP_004834
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Pathways
- Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
Target
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