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TCF4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Recombinant TCF4 protein expressed in HEK-293 Cells.
Catalog No. ABIN2733362
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 11 to 12 Business Days

Quick Overview for TCF4 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2733362)

Target

See all TCF4 Proteins
TCF4 (Transcription Factor 4 (TCF4))

Protein Type

Recombinant

Origin

  • 8
  • 1
  • 1
  • 1
Human

Source

  • 4
  • 3
  • 2
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 1

    Purification tag / Conjugate

    This TCF4 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human TCF4 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    Expression System
    Conjugate
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    Expression System HEK-293 Cells
    Conjugate His tag
    Origin Human
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    TCF4 (Transcription Factor 4 (TCF4))

    Alternative Name

    Tcf4

    Background

    This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to > 50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.

    Molecular Weight

    71.6 kDa

    NCBI Accession

    NP_001077431

    Pathways

    WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
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