TGFB3 Protein (Myc-DYKDDDDK Tag)
Quick Overview for TGFB3 Protein (Myc-DYKDDDDK Tag) (ABIN2733499)
Target
See all TGFB3 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This TGFB3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TGF-beta-3 (TGFB3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))
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Alternative Name
- Tgf-beta-3 (Tgfb3)
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Background
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1.
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Molecular Weight
- 44.7 kDa
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NCBI Accession
- NP_003230
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Pathways
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
Target
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