TIA1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for TIA1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2733699)
Target
See all TIA1 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This TIA1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TIA1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-214) protein (GST tag)
TIA1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 2-285) protein (His tag)TIA1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
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Alternative Name
- Tia1
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Background
- The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
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Molecular Weight
- 42.8 kDa
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NCBI Accession
- NP_071505
Target
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