TIMELESS Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2733738

Product Details

Target: TIMELESS (Timeless Homolog (TIMELESS))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This TIMELESS protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Timeless (Tim) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TIMELESS (Timeless Homolog (TIMELESS))

Alternative Name: Timeless (Tim) (TIMELESS Products)

Synonyms: TIM Protein, TIM1 Protein, hTIM Protein, C77407 Protein, Debt69 Protein, tim Protein, CG3234 Protein, Dmel\\CG3234 Protein, Ritsu Protein, Tim Protein, dTIM Protein, dTim Protein, dtim Protein, mel_tim Protein, rit Protein, tim1 Protein, XTimeless1 Protein, timeless Protein, timelessb Protein, TIMELESS Protein, MXC20.14 Protein, MXC20_14 Protein, htim Protein, im:6903167 Protein, wu:fa95g04 Protein, wu:fd23d07 Protein, timeless circadian regulator Protein, timeless circadian clock 1 Protein, timeless Protein, timeless circadian clock Protein, timeless circadian clock S homeolog Protein, timeless family protein Protein, TIMELESS Protein, Timeless Protein, tim Protein, timeless.S Protein, Tim Protein, ATIM Protein, timeless Protein, LOC100328917 Protein

Background: The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders.

Molecular Weight: 138.5 kDa

NCBI Accession: NP_003911

Pathways: Protein targeting to Nucleus, Photoperiodism