STING/TMEM173 Protein (Myc-DYKDDDDK Tag)
Quick Overview for STING/TMEM173 Protein (Myc-DYKDDDDK Tag) (ABIN2733879)
Target
See all STING/TMEM173 (TMEM173) ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This STING/TMEM173 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TMEM173 / STING protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Transmembrane Protein 173 (TMEM173) (AA 99-330) protein (Fc Tag)
TMEM173 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Transmembrane Protein 173 (TMEM173) (AA 147-357) protein (His-IF2DI Tag)TMEM173 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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Alternative Name
- Tmem173,sting
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Background
- This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
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Molecular Weight
- 42 kDa
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NCBI Accession
- NP_938023
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Pathways
- Activation of Innate immune Response
Target
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