STING/TMEM173 Protein (SUMO Tag,His tag)
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- Target See all STING/TMEM173 (TMEM173) Proteins
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This STING/TMEM173 protein is labelled with SUMO Tag,His tag.
- Purpose
- Recombinant Human STING/TMEM173 Protein (Sumo & His Tag)
- Sequence
- Val155-Val341
- Characteristics
- Recombinant Human STING is produced by our E.coli expression system and the target gene encoding Val155-Val341 is expressed with a 6His, Sumo tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TMEM173 Protein
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Transmembrane Protein 173 (TMEM173) (AA 1-379) protein (rho-1D4 tag)
Crystallography grade TMEM173 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Transmembrane Protein 173 (TMEM173) (AA 147-357) protein (His-IF2DI Tag)TMEM173 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Transmembrane Protein 173 (TMEM173) (AA 137-379) protein (His tag)Crystallography grade TMEM173 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Transmembrane Protein 173 (TMEM173) (AA 136-378) protein (His tag)Crystallography grade TMEM173 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Transmembrane Protein 173 (TMEM173) (AA 1-378) protein (rho-1D4 tag)Crystallography grade TMEM173 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Alternative Name
- STING/TMEM173 (TMEM173 Products)
- Synonyms
- ERIS Protein, MITA Protein, MPYS Protein, NET23 Protein, STING Protein, 2610307O08Rik Protein, Mita Protein, RGD1562552 Protein, transmembrane protein 173 Protein, TMEM173 Protein, Tmem173 Protein
- Background
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Background: Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a C-terminal cytoplasmic domain (aa 174-379). It ubiquitously expressed in skin endothelial cells, alveolar type 2 pneumocytes, bronchial epithelium and alveolar macrophagesand. Its subunit structure associated with the MHC-II complex and Interacts with DDX58/RIG-I, MAVS and SSR2, RNF5 and TRIM56 along with TBK1. This type of protein often uses as facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon.
Synonym: Stimulator of interferon genes protein,TMEM173,Mediator of IRF3 activation,sting,
- Molecular Weight
- 33.8 kDa
- UniProt
- Q86WV6
- Pathways
- Activation of Innate immune Response
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