TP53I3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for TP53I3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2734083)
Target
See all TP53I3 ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This TP53I3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TP53I3 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) protein (His tag)
custom-made TP53I3 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) protein (GST tag)TP53I3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Tumor Protein P53 Inducible Protein 3 (TP53I3) (AA 1-332) protein (His tag)TP53I3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Tumor Protein P53 Inducible Protein 3 (TP53I3) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)TP53I3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))
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Alternative Name
- Tp53i3
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Background
- The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 35.4 kDa
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NCBI Accession
- NP_004872
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Pathways
- p53 Signaling
Target
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