TRAF1 Protein (Myc-DYKDDDDK Tag)
Quick Overview for TRAF1 Protein (Myc-DYKDDDDK Tag) (ABIN2734111)
Target
See all TRAF1 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This TRAF1 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TRAF1 / EBI6 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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TNF Receptor-Associated Factor 1 (TRAF1) (AA 1-409) protein (His tag)
custom-made TRAF1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
TNF Receptor-Associated Factor 1 (TRAF1) (AA 1-416) protein (GST tag)TRAF1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
TNF Receptor-Associated Factor 1 (TRAF1) (AA 266-416) protein (His tag)TRAF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS
TNF Receptor-Associated Factor 1 (TRAF1) (AA 266-416) protein (His-IF2DI Tag)TRAF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
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Alternative Name
- Traf1,ebi6
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Background
- The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene.
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Molecular Weight
- 46 kDa
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NCBI Accession
- NP_005649
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Pathways
- NF-kappaB Signaling, Apoptosis, Cell-Cell Junction Organization, Asymmetric Protein Localization
Target
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