TCOF1 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2734193

Recombinant TCOF1 protein expressed in HEK-293 Cells.

Quick Overview for TCOF1 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2734193)

Target: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 3

Purification tag / Conjugate: This TCOF1 protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human Treacle protein / TCOF1 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Alternative Name: Treacle Protein,tcof1

Background: This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 96.6 kDa

NCBI Accession: NP_001008657