TRIM68 Protein (Myc-DYKDDDDK Tag)
Quick Overview for TRIM68 Protein (Myc-DYKDDDDK Tag) (ABIN2734291)
Target
See all TRIM68 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This TRIM68 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TRIM68 / RNF137 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Tripartite Motif Containing 68 (TRIM68) (AA 1-485) protein (His tag)
custom-made TRIM68 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tripartite Motif Containing 68 (TRIM68) (AA 1-485) protein (His tag)custom-made TRIM68 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Tripartite Motif Containing 68 (TRIM68) (AA 181-280) protein (GST tag)TRIM68 Origin: Human Host: Wheat germ Recombinant AP, AA, ELISA, WB
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TRIM68 (Tripartite Motif Containing 68 (TRIM68))
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Alternative Name
- Trim68,rnf137
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Background
- This gene encodes a member of the tripartite motif-containing protein family, whose members are characterized by a 'really interesting new gene' (RING) finger domain, a zinc-binding B-box motif, and a coiled-coil region. Members of this family function as E3 ubiquitin ligases and are involved in a broad range of biological processes. This gene regulates the activation of nuclear receptors, such as androgen receptor, and has been implicated in development of prostate cancer cells, where its expression increases in response to a downregulation of microRNAs. In addition, this gene participates in viral defense regulation as a negative regulator of interferon-beta. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 56.1 kDa
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NCBI Accession
- NP_060543
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Target
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