TRIOBP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2734308

This Recombinant TRIOBP protein is produced in HEK-293 Cells.

Quick Overview for TRIOBP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2734308)

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Protein Characteristics: Transcript Variant 2

Purification tag / Conjugate: This TRIOBP protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human TRIOBP / TARA (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Alternative Name: Triobp,tara

Background: This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).

Molecular Weight: 47.4 kDa

NCBI Accession: NP_619538

Pathways: Regulation of Actin Filament Polymerization