TSHZ3 Protein (Myc-DYKDDDDK Tag)
Quick Overview for TSHZ3 Protein (Myc-DYKDDDDK Tag) (ABIN2734445)
Target
See all TSHZ3 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This TSHZ3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human TSHZ3 / ZNF537 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))
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Alternative Name
- Tshz3,znf537
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Background
- This gene encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of this gene and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients.
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Molecular Weight
- 118.4 kDa
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NCBI Accession
- NP_065907
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Pathways
- Regulation of Muscle Cell Differentiation
Target
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