UBTF Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Quick Overview for UBTF Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2734925)
Target
See all UBTF ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 2
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Purification tag / Conjugate
- This UBTF protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human UBTF / UBF (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- UBTF (Upstream Binding Transcription Factor, RNA Polymerase I (UBTF))
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Alternative Name
- Ubtf,ubf
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Background
- This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.
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Molecular Weight
- 84.8 kDa
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NCBI Accession
- NP_001070151
Target
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