UNC13D Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2735014

This Recombinant UNC13D protein is expressed in HEK-293 Cells.

Quick Overview for UNC13D Protein (Myc-DYKDDDDK Tag) (ABIN2735014)

Target: UNC13D (Unc-13 Homolog D (UNC13D))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Product Details

Purification tag / Conjugate: This UNC13D protein is labelled with Myc-DYKDDDDK Tag.

Characteristics:

• Recombinant human UNC13D protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: UNC13D (Unc-13 Homolog D (UNC13D))

Alternative Name: Unc13d

Background: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Molecular Weight: 123.1 kDa

NCBI Accession: NP_954712

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process