USP20 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
This Recombinant USP20 protein is produced in HEK-293 Cells.
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Catalog No. ABIN2735100
$1,112.40
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20 μg
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United States
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Quick Overview for USP20 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2735100)
Target
See all USP20 Proteins
USP20
(Ubiquitin Specific Peptidase 20 (USP20))
Protein Type
Recombinant
Origin
Human
Source
HEK-293 Cells
Application
Antibody Production (AbP), Standard (STD)
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This USP20 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human USP20 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Ubiquitin Specific Peptidase 20 (USP20) (AA 1-913) protein (GST tag)
USP20 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
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Alternative Name
- Usp20
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Background
- This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein.
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Molecular Weight
- 101.7 kDa
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NCBI Accession
- NP_006667
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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