VPREB3 Protein (Myc-DYKDDDDK Tag)
Quick Overview for VPREB3 Protein (Myc-DYKDDDDK Tag) (ABIN2735411)
Target
See all VPREB3 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This VPREB3 protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human VPREB3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- VPREB3 (Pre-B Lymphocyte 3 (VPREB3))
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Alternative Name
- Vpreb3
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Background
- The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas.
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Molecular Weight
- 13.5 kDa
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NCBI Accession
- NP_037510
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Pathways
- Production of Molecular Mediator of Immune Response
Target
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