VPS4A Protein (Myc-DYKDDDDK Tag)
Quick Overview for VPS4A Protein (Myc-DYKDDDDK Tag) (ABIN2735431)
Target
See all VPS4A ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This VPS4A protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human VPS4A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) (AA 1-437) protein (GST tag)
VPS4A Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Vacuolar Protein Sorting-Associated Protein 4A (VPS4A) (AA 1-437) protein (His tag)VPS4A Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))
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Alternative Name
- Vps4a
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Background
- The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16 the gene for the other resides on chromosome 18.
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Molecular Weight
- 48.7 kDa
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NCBI Accession
- NP_037377
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Pathways
- Microtubule Dynamics, CXCR4-mediated Signaling Events
Target
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